MUTANT STRAINS OF NEUROSPORA DEFICIENT IN AMINATING ABILITY
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چکیده
منابع مشابه
Cysteine Mutant Strains of Neurospora'
UTANT strains of Neurospora crassa that are unable to utilize inorganic sulfur, but which are capable of growth on minimal medium supplemented with either cysteine or methionine, are obtained readily. It is surprising, therefore, that little genetic information has been available for cysteine mutants of Neurospora, other than those located in linkage group VI (STADLER 1956a,b, 1959a,b; STADLER ...
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Until recently there has been no demonstrated case in Neurospora in which the loss of activity of an essential enzyme could be attributed to gene mutation. It has been assumed from indirect evidence1 that gene mutations do cause such losses and thereby result in “blocks” of essential biochemical reactions. The products of the “blocked” reactions thus become essential growth substances for the m...
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The present studies were undertaken to determine the extent to which the phospholipid composition of Neurosporn crama can be altered by mutations studied in conjunction with controlled supplementation. Previous work in this laboratory has shown that a mutation involving an enzyme concerned with lecithin synthesis can result in a lecithin-deficient strain (1, 2). The methylation of phosphatidyle...
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25 Matsuo, Y., and D. M. Greenberg, J. Biol. Chem., 234, 516 (1959). 26 Loiselet, J., and F. Chatagner, Biochim. Biophys. Acta, 89, 330 (1964). 27 Jolles-Bergeret, B., and F. Chatagner, Arch. Biochem. Biophys., 105, 640 (1964). 28 Matsuo, Y., and D. M. Greenberg, op. cit., 230, 561 (1958). 29 Binkley, F., and M. Boyd, J. Biol. Chem. 217, 67 (1955). 30 Laster, L., G. L. Spaeth, S. H. Mudd, and J...
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Inhibitions of the growth of organisms by closely related structural analogues of several water-soluble vitamins are well known. Similar types of antagonism in the case of purine and pyrimidine metabolites are those between the purine bases, adenine and guanine, and benzimidazole (1) and between barbituric acid and uracil in the growth of Staphylococcus aureus (2). In such cases the antagonism ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1950
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)56527-3